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February 23, 2018 at 2:00 pm #9393
This is a superb review of the histopathologic findings in Celiac disease. It may be that it is assumed that serologic testing would precede performance of endoscopy, but a statement specifically recommending testing for IgA anti-tissue transglutaminase (TTG) and IgG and IgA anti-deamidated gliadin prior to endoscopy could help exclude unlikely cases. Further, testing for HLA-DQ2 and HLA-DQ8 are useful for excluding unlikely candidates for the disease.