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Case Study of the Month 3

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Case Study of the Month 2

PDF of this month’s case

2012 ASCP Meeting Evaluation of Colon Cancer Cases…Everything You Ever Wanted to Know…and More

Speakers:

Rhonda Yantiss, MD

Mary Kay Washington, MD

Alyssa M. Krasinskas, MD, FASCP

Robert M. Najarian, MD

Steven Wexner, MD

Mariana Berho, MD

Description:

 

Members of the Rodger C. Haggitt Gastrointestinal Pathology Society Education Committee felt that a multidisciplinary discussion of colorectal cancer may be helpful to practicing surgical pathologists. Recent changes to the AJCC TNM Cancer Staging Manual, the WHO Tumor Classification, and the CAP guidelines have led to confusion and inconsistent reporting practices among pathologists. Advanced surgical techniques have changed the way patients with colon cancer are managed, yet many pathologists, residents, and pathology assistants do not understand the anatomy of resultant specimens. The topics of discussion will include: 1. Surgical Management of Rectal Cancer: What Pathologists Need to Know—Steve Wexner 2. Pathologic Evaluation of Malignant Polyps–Robert Najarian 3. Pathologic Staging Issues: Applying Criteria of the AJCC 7th edition–Kay Washington 4. Ancillary Testing of Colon Cancer: The Routine and Esoteric–Alyssa Krasinskas

Learning Objectives:

  • Understand factors that determine the type of surgical approach used to treat colon cancer patients and know how to handle resection specimens appropriately.
  • Apply pathologic staging criteria accurately to surgical and endoscopic resection specimens, such that clinicians can make informed management decisions.
  • Interpret results of ancillary tests used to determine treatment strategies for cancer patients and identify potential at-risk family members.

Case Study of the Month 1

PDF of this month’s case

IAP 2012, Capetown, South Africa Gastrointestinal Tract Slide Seminar: An Umcimbi of GI Pathology

CASE HISTORIES – 2012 IAP GI PATHOLOGY SLIDE SEMINAR (AN UMCIMBI OF GI PATHOLOGY)

Meeting Handouts – Members can access meeting handouts here. gips-iap

CASE 1

Dr. Tomas Slavik (Ampath Pathology Laboratories & Extraordinary Lecturer, University of Pretoria, South Africa)

71 year old female who presented with diarrhoea and weight loss. Upper endoscopy revealed hypertrophic gastric rugae and irregularly nodular to polypoid mucosa. Biopsies were received, marked as: 1. gastric mucosa/polyps, 2. duodenal mucosa/polyps.

CASE 2

Dr. Andrew Clouston (Envoi Specialist Pathologists & Associate Professor of Pathology, University of Queensland, Australia)

A 67 year old male with a history of fistula-in-ano and recurrent perianal abscess. An initial biopsy showed gelatinous material macroscopically. In this resected specimen, the anorectal muocsa had scarring but was otherwise smooth.

CASE 3

Prof. Marco Novelli (Professor of Pathology, University College London Medical School, United Kingdom)

38 year old male with a sigmoid tumour, lymph node and lung metastases, as well as a presacral lesion. No reponse to Glivec was obtained. Sections provided from the sigmoid tumor – H&E and immunoperoxidase stains (CD117, CD34).

CASE 4

Prof. Elizabeth Montgomery (Professor of Pathology and Oncology, Johns Hopkins University, USA)

Duodenal biopsy received with the following history: “diarrhoea, rule out coeliac disease”.

CASE 5

Prof. Claude Cuvelier (Professor of Pathology, University of Gent, Belgium).

CASE 6

Prof. David Owen (Professor of Pathology, University of Vancouver, Canada)

24 year old male with subacute large bowel obstruction, for which right hemicolectomy was performed. The proximal colon and caecum were dilated and filled with faecal material.

Meeting Handouts – Members can access meeting handouts here.

2012 Abstract Award Winner

Aatur Singhi, Johns Hopkins Hospital

Acinar Cell Cystadenoma of the Pancreas: A Benign Neoplasm or Non-Neoplastic Ballooning of Ducts

abstract-award-winner-aatur-singhiRunner-Up Presentations:

David Hernandez Gonzalo, Cleveland Clinic: Hirschsprung’s Disease and Calretinin in Inadequate Biopsies

Bing Ren, University of Rochester Medical Center: MACC1, a Potential Diagnosis Marker for Early Stage Colorectal Cancer

2012 USCAP Companion Meeting: Gastrointestinal Manifestations of Systemic Diseases: Vancouver

Gastrointestinal Manifestations of Systemic Diseases

Sunday, March 18, 1:30 PM

Vancouver Convention Center

Room:

Moderator: Rhonda Yantiss, Cornell University, New York NY

GI Infections in the Immunocompromised Host.

Laura Lamps, University of Arkansas, Little Rock, AK

Drug-induced Injury of the GI Tract.

David Owen, University of British Colombia, Vancouver, BC

Immunodeficiency Syndromes that Mimic Primary GI Disorders.

Susan Abraham, MD Anderson Medical Center, Houston, TX

Vasculitis.

John Hart, University of Chicago, Chicago, IL

Rodger C. Haggitt Memorial Lecture:

Cutaneous Manifestations of GI Disorders and Dermatologic Diseases that Affect the GI Tract

Bruce Smoller, University of Arkansas, Little Rock, AK

USCAP 2012 Rodger C. Haggitt Gastrointestinal Pathology Society Forum

Evidence-Based Medicine In The Practice Of Gastrointestinal Pathology

Saturday, March 17, 3-5 PM, Vancouver Convention Center, Room 211-214

Agenda

  • 3:00-3:15 Concrete Billing Issues Directly Related To GI Pathology – Jeff Jacobs
  • 3:15-3:25 Evidence For Use Of “Up Front” Ancillary Stains – Rhonda Yantiss
  • 3:25 – 3:40 Evidence For Use Of Molecular Testing As A Diagnostic Or Prognostic Tool (Who, What, When, Where, And Why?) – Stan Hamilton
  • 3:40 – 4:00 When The Trip From Bench (Microscope) To Bedside Goes Awry: “Illogical Intellectual Drift” – Dale Snover
  • 4:00 – 5:00 Panel Discussion: Aim To Address The Issue Of Policing Ourselves To Produce Better Literature

Moderator: Jim Crawford

Panelists: Wade Samowitz, Marie Robert, And Larry Burgart

Meeting Handouts – Members can access meeting handouts here.

2012 GIPS Travel Award Winner

William W Bivin, Allegheny General Hospital

w-bivin-travel-award-winner-2012The Roger Haggitt Gastrointestinal Pathology Society (GIPS) would like to invite applications for the “GIPS Travel Award”. Each year, this award is given by GIPS to pathology residents who are interested in gastrointestinal pathology. The award comprises of free registration to selected GI courses and a sum of $500 to cover travel-related expenses.

Membership Application

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e-Learning

e-Journal Club
Exploring Rarities: from Langerhans to HPV in the Gut

February 12, 2025 2:00 pm EST

Register Here

Presenters and their articles:

Ebubekir Ucar, MD
PGY2, Northshore University Hospital
Northwell Health, New York

Bauer AH, Alkhateeb KJ, Agoston AT, Odze RD, Joshi MG, Huffman BM, Enzinger P, Perez K, Deshpande V, Cleary JM, Wee JO, Dong F, Zhao L. Transcriptionally Active Human Papillomavirus Infection in a Minority of Esophageal Squamous Cell Carcinomas in North America. Am J Surg Pathol. 2024 Jul 1;48(7):883-889. doi: 10.1097/PAS.0000000000002235. Epub 2024 May 10. PMID: 38726899.

Rashmi Tondon, MD PDCC
Associate Professor of Pathology,
Hospital of the University of Pennsylvania, PA

Hu S, Graham RP, Choi WT, Wen KW, Putra J, Chen W, Lin J, Gonzalez IA, Panarelli N, Liu Q, Zhao L, Gong S, Mejia-Bautista M, Escobar DJ, Ma C, Shalaby A, Du X, Kang LI, Zhang W, Chen X, Ding X, Chen HH, Ye Z, Pezhouh MK, Liao X, Liu Y, Yang Z, Alpert L, Hart J, Goldblum JR, Allende D, Zheng W, Gonzalez RS, Wang HL, Zhang X, Liu X, Longacre T, Westerhoff M, Xue Y. Clinicopathologic Features of Gastrointestinal Tract Langerhans Cell Histiocytosis. Mod Pathol. 2024 Sep;37(9):100543. doi: 10.1016/j.modpat.2024.100543. Epub 2024 Jun 17. PMID: 38897453.